Laboratory — Genetic Testing

89290

Embryo Biopsy — 1–5 Embryos (PGT)

Biopsy of oocyte polar body or embryo for preimplantation genetic testing — 1 to 5 embryos. This code covers the embryology lab component of the biopsy procedure. Genetic analysis (chromosomal or molecular) is billed separately by the reference genetics laboratory.

Billing Notes

89290 covers biopsy of up to 5 embryos. For 6 or more embryos, use 89291. These codes reflect the embryology labor for biopsy only — the genetic analysis charges (81228, 81229, 81479) are typically billed directly by the genetics lab to the patient or payer.

Diagnosis Codes

N96 (recurrent pregnancy loss), Z13.88 (genetic screening), Q95.x (chromosomal rearrangement)

Common Denial Reasons

  • 89291 billed when embryo count is ≤5
  • Biopsy and genetic analysis both billed by the clinic (split billing required)
  • Missing documentation of embryo count biopsied

Payer Notes

Many commercial payers cover PGT-A for specific indications (advanced maternal age ≥38, recurrent miscarriage, prior aneuploid pregnancy). PGT-M and PGT-SR coverage requires strong prior authorization with genetic counseling documentation.

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